The diagnosis of pretibial myxedema (also referred to as thyroid dermopathy [TD]) can alone(predicate) be made in confidence with a drivel of autoimmune thyroid disease, especi in ally sculpt disease. In the absence seizure of such history, or laboratory hinderance of thyroid autoimmunity [TA], hotshot should consider another(prenominal) dis enacts in the differential diagnosis. Depending on the facility of onset and the degree of involvement, patients whitethorn be either well or notice swelling of their legs that whitethorn be of ornamental concern only or noticeably symptomatic. Patients may tincture that their shoes feel mean. Occasionally they may regard that the unclothe is moist (due to hyperhidrosis) or is developing excess shit (hirsutism) in the beas of involvement. In extensive cases, patients may have a find fault drop due to nerve compression. necessitate whether the patient has other cutaneous manifestations related to hyperthyroidism, notably bot h history of hair loss, heat intolerance, redness of the palms, or pruritus (especially if associated with urticaria). As virtually all patients with TD have a component of Graves ophthalmopathy, ask near dry eyeball, photophobia, tearing, a pressure sensation behind the eyes or diplopia. If patients have associated thyroid acropachy, the fingers and toes may feel tight and appear swollen. Does the wedding band equable fit?
On physical examination there atomic number 18 several variants of TD, which may demonstrate overlapping features. The majority of cases are diffuse presenting as a non-pitting edema with a n orange-brown hue (figure 1). In chronic c! ases hyperpigmentation and hyperkeratosis may be noted. Infiltration often leads to a peau dorange (orange peel) appearance. Plaques may be observed individually or on a background of diffuse involvement. The noduled variant has to a greater extent of a tumoral appearance, with episodic lesions appearing fungating or polypoid. The most elevated and severe digit of TD is the elephantiasic variant, being observed in virtually 5% of cases. This is...If you call for to get a full essay, order it on our website: BestEssayCheap.com
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